Assay(%)..............................................>98

Melting Poit(℃）.................................49-51

General description

Cyclophosphamide (CYC) is a cytotoxic alkylating agent.^[1] It is activated by the cytochrome P-450 enzyme system in the liver.^[2] It has immunomodulatory functionality and inhibits humoral and cellular immunity.^[3]

Application

Cyclophosphamide monohydrate has been used:
• to test its antitumor effect on TC-1 tumor cells^[4]
• as a component of multidrug solution for isolation of resistant human burkitt lymphoma cell line^[5]
• in testing antitumor immunity in mouse tumor cell lines^[6]