(±)-C75
更新：2017/9/15 10:30:27
| 中文名: | (±)-C75 | ||
| 英文名: | tetrahydro-4-methylene-2R-octyl-5-oxo-3S-furancarboxylic acid | ||
| 別名: | |||
| CAS No.: | 191282-48-1 | 級別: | |
| 分子式: | C14H22O4 | 分子量: | 254.3 |
訂購信息
| 貨號 | 規(guī)格 | 價格 | 品牌 |
| 10005270-10mg | 10mg | 2950 | GBCBIO |
| 10005270-10mg | 10mg | 3550 | Cayman |
產(chǎn)品介紹
| Inhibition of fatty acid synthase (FAS) by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines.1 (±)-C75 is a stable inhibitor of FAS that leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.2 (±)-C75 is also cytotoxic to many human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway |
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