Folic acid antagonist. Amethopterin is actively transported into cells by the folate transporter. In the cell, it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate red">
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              Amethopterin Hydrate

              Update:2014/11/25 0:59:40

                Item:Amethopterin Hydrate
                Synonym:MTX ; 4-Amino-10-methylfolic acid; Methylaminopterin; (+)-Amethopterin hydrate
                CAS No.:59-05-2Special Grade:Biotech Grade
                Formula:C20H22N8O5M.W.:454.44
              Order
                Product No.SizePriceBrand
                A6770-10mg10mg160GBCBIO
                A6770-50mg50mg450GBCBIO
                A6770-1g1g7855Sigma
              Introduction
                Purity (HPLC)(%)..............................≥98.5
                Water (Karl Fisher) (%).........................≤12

                Folic acid antagonist. Amethopterin is actively transported into cells by the folate transporter. In the cell, it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate red

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