Aminopterin
Update:2014/10/4 16:37:20
| Item: | Aminopterin | ||
| Synonym: | 4-Aminofolic acid; 4-Aminopteroyl-L-glutamic acid; 4-Amino-PGA | ||
| CAS No.: | 54-62-6 | Special Grade: | Biotech Grade |
| Formula: | C19H20N8O5 | M.W.: | 440.41 |
Order
| Product No. | Size | Price | Brand |
| A1784-10mg | 10mg | 540 | GBCBIO |
| A1784-50mg | 50mg | 2453 | GBCBIO |
| A1784-50mg | 50mg | 1877 | Sigma |
Introduction
| Purity (TLC)(%).........................~98.0 Water (2.5mol/mol) (%)................≤9.3 |
| Folic acid antagonist. Aminopterin is actively transported into cells by the folate transporter. In the cell, it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase that, in turn, binds to dihydrofolate reductas |
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